Clone A16085H
Regulatory Status RUO
Other Names VEGFR2, KDR
Isotype Mouse IgG1, κ
Description CD309, also known as VEGF-R2, KDR, and Flk-1 (mouse), is a type I transmembrane
glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase
2025-05-19receptors. Human VEGF-R2 is mainly expressed by endothelial cells, embryonic tissues, and megakaryocytes. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGF-R2 include VEGF-A, VEGF-C, and VEGF-D splice isoforms. Activation of VEGF-R2 with its ligands results in the receptor dimerization and autophosphorylation, stimulating endothelial cell proliferation and migration.
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Verified Reactivity | Human |
Antibody Type | Monoclonal |
Host Species | Mouse |
Immunogen | Recombinant Human VEGFR2-Fc Chimera |
Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA) |
Preparation | The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. |
Concentration | Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.) |
Storage & Handling | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
Application | |
Recommended Usage |
cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood. |
Excitation Laser | Blue Laser (488 nm) Green Laser (532 nm)/
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